THE ACTION OF CARDIAC GLYCOSIDES ON AUTONOMIC GANGLIA

The action of cardiac glycosides on experimental auricular flutter.

Question of norepinephrine release in the action of cardiac glycosides.

Contraction dependency of the positive inotropic action of cardiac glycosides.

The concept that the positive inotropic effect of cardiac glycosides is dependent on the contractile state of the myocardium was tested. Isolated left atria of rabbits, when driven electrically at 15, 30, 60 and 120/min (at 30, 33, or 37°C), responded to ouabain (1 yug/ml) in proportion to the number of contractions and not to the time of exposure or frequency of drive. Contraction-related effe...

Differential selectivity of cardiac neurons in separate intrathoracic autonomic ganglia.

Analyses of activity generated by neurons in middle cervical or stellate ganglia versus intrinsic cardiac ganglia were performed to determine how neurons in different intrathoracic ganglia, which are involved in cardiac regulation, interact. Discharges of 19% of intrathoracic extracardiac neurons and 32% of intrinsic cardiac neurons were related to cardiodynamics. Epicardial touch increased the...

The action of several cardiac glycosides on conduction velocity and ventricular excitability in the dog heart.